According to Weekly Shounen Magazine, a new TV anime series of Hajime no Ippo was announced. It will start airing in January 2009.
The first series was aired from 2000 to 2002 and established a record high average rating as an "after-midnight" anime.
Source: Scan of Weekly Shounen Magazine
The new series will be resumed from the last special episode "Hajime no Ippo Champion Road (Ippo v.s. Sanada Kazuki match)" aired on Apr 18 2003.
The new character designs were revealed.
Scan of the Weekly Shounen Magaziner