Perhaps my review here will be a bit prejudiced with what I know from the manga.
Story;
It's not some overly crazy plot like in other harems, where somehow all the girls somehow are fawning over that one random useless dude.
The story is basically a flashback: The very beginning spoilers you that he will get married to one of them, making you keep that in mind during the whole development.
The main premise of the story is rather simple - Fuutarou Uesugi, a poor top student, is asked to tutor the Nakano quintuplets. They start off with having no interest in being tutored by him (and no interest in him as a person too), and since everyone of them has very differing personalities and interests, he has to approach each one differently to get them to accept him.
Characters;
Again, when comparing it to other harems I find the characters quite likeable. The male main isn't some useless crybaby. He's clever, he's not scared to talk back and isn't completely paralyzed when standing in front of a girl.
The female characters aren't as shallow as in other harems either. They each have their own character traits, and their own relationship to the male main, some starting off more friendly, some less. That allows for some actual development between the characters in the future.
Art/Sound;
Nothing to complain here, nothing extraordinary either.
Enjoyment;
I like the comedy aspect of it. It doesn't feel forced or tries to build in some silly dialogue just to get a joke in. It's pretty light, simply some funny moments in between.
Overall;
I think it is an enjoyable anime. Although, since it's based on an somewhat long ongoing manga I doubt that there will be a conclusive ending to it.
