The fearsome foursome continue their journey west towards Shangri-La, encountering new challenges and new adventures along the way. Their legend precedes them, but not always in the way one might expect. The Minus Wave that apparently drove all the youkai in the land mad looks like it might have missed one, as Sanzou, Gojou, Hakkai and Gokuu meet a lone guardian and the band of children he cares for. Fear and misunderstanding run throughout this particular leg of the journey, including between the members of the Sanzou group!
Saiyuuki Reload had nine volumes published in English by Tokyopop from August 9, 2005 to January 6, 2009, before the publisher became defunct. The final volume was published by Singaporean based publisher Chuang Yi in October 2010.