Tenchi Souzou Design-bu

Both anime are educutional anime that teach about animals in a comedic way. Both are great comedy, so whether you just want a good laugh or learn about animals, I recommend both anime. Main difference is in Muranase the animals are antropomorphized and has moe wolf-girls and cat-girls etc., while Tenchi Souzou has normal humans and normal animals.  

Two comedies centering around animals, both feel quite similar with how they more or less talk about different animals and focus on specific species at times. Differences would be that Tendebu is about the creation of animals and Kawaisugi Crisis is about discovering different cute pets. 

Both anime take references from real life and use it as plot device. So in essence, you can learn something about human body (Hataraku Saibo) or about some animals (Design-bu). If you want to have fun and some real life facts, here you go, these anime make an attempt in doing so! How useful it is is up to you, of course. 

Both series are comedies that thrive on being as silly as possible. Like how Cuticle Tantei Inaba is about stopping the crimes of an Italian Mafia Boss (who is a goat), and Tenchi Souzou Design-bu is about creating animals with the silliest process possible. 

I watched both these anime without looking anything up about them beforehand, and the great thing is...both anime turned out to be hilarious. Besides the fact that they are great comedy, they are both working-life anime where the characters design creatures, in Kaijin Kaihatsu they design monsters while in Tenchi Souzou they design animals (and some monsters as well). The anime show the hardships of having a job very well, and the characters often experience failure while doing their job. Tenchi Souzou is more educational and has a small cast without cute girls, Kaijin Kaihatsu has plenty. Both have woke themes (character in wrong gendered body) 

Both are stories about people having a hard time at work, but loving their job anyway, and both shows teach us stuff about the anime's theme in a very fun way. The jokes are very similar.