We've seen this before: a loser adult man gets isekai'd and builds a loli harem. But is there more to it? As it turns out: no, that's all there is.
Even trying to ignore the questionable fanservice and the obsessing over little girls, thinking that "maybe there's a decent story behind all this", it ends up being just a waste of time.
Characters are as bland as they get. Not even Kazuma's voice actor could make the MC interesting. Episodes feature generic plots while slowly increasing the size of the pharmacist's harem over time.
Character designs are mediocre, most of the effort seems to have gone into designing bloomer panties and empty personalities that fawn over the MC.
Animation itself is nothing to write home about. It works decently along with the soundtracks.
Overall, the generic escapist fantasy of a loser man that is suddenly loved by everyone in an imaginary world coud be decent when done right, but with such a lack of substance in this case where you even question whether this is an isekai or not, even fans of generic isekai might find this one to be too much of a letdown.