Mazinger Angels chronicles the adventures of four women who pilot giant robots in the Mazinger vein. The concept is a spoof on the late 70's and early 80's popular TV series Charlie's Angels.
Three of the robots, Aphrodite A, Diana A and Minerva X are from the original Mazinger Z series, while Venus A is from the Great Mazinger series. Their pilots are also traditional characters from Go Nagai's universe, Sayaka Yumi and Jun Hono from Mazinger Z and Great Mazinger respectively, and Hikaru Makiba and Maria Fleed from Grendizer.
The style of the manga highlights the sex appeal of both the characters and the mechas, sometimes similarly to the way Aika's female characters are shown.