After a mysterious spaceship crashes into Earth, humanity realizes that they are not alone. Fearing a potential threat from space, the world pushes aside their nationalism, conflicting interests, and cultural differences, unifying under the banner of the United Nations. The newly formed UN forces decide to repurpose the alien spacecraft, naming it SDF-1 Macross. Unfortunately, on the day of its maiden voyage, a fleet of spaceships belonging to a race of aliens known as Zentradi descend upon Earth, and the SDF-1 Macross, acting of its own accord, shoots down the incoming squadron, sparking an intergalactic war.
In an attempt to escape, the Macross tries to launch itself into the Moon's orbit, but the ship—as well as the city was in—is teleported to the far reaches of space. Caught up in the mess are Hikaru Ichijou, a free-spirited acrobatic pilot, and Minmay Lynn, an aspiring idol. Together, alongside Macross's bridge officer Misa Hayase, they experience an epic journey rife with grief and drama as they begin their trek back to Earth, facing with the cruelties of war along the way.
Choujikuu Yousai Macross: The First is an adaptation of studio Tatsunoko Pro's original TV anime series Choujikuu Yousai Macross. It is an alternate re-telling of the events drawn by Haruhiko Mikimoto, the character designer of the original series.