Shin no Nakama ja Nai to Yuusha no Party wo Oidasareta node, Henkyou de Slow Life suru Koto ni Shimashita

Main protag is kicked out of their party for being useless, but they end up actually being decently capable, then settle down in a little town, and have a cute "gifted' girl with a huge crush on them. Big difference would be that Chillin' in my 30s' party were the bad guys, and is a bit more focused on the comedy. 

Both MC's run an apothecary in a slow life isekai. Cheat Kusushi is very fluffy with its vibrant pastel colour palette and lighthearted mood whereas Shin no Nakama has a lot more going on in moods but with a heavier plot in turn making it more serious compared to. Shin no Nakama has intense, grueling, and violent scenes as each episode continues on its plot whereas Cheat Kusushi is full on fluff in its more episodic storytelling. There is a little bit of drama in some episodes of Cheat Kusushi and Shin no Nakama does have its share of lighthearted banter as well so there is a bit of balance in both, despite them leaning more in the opposite direction of moods in both. read more 

Both of them are well written stories about a man and a woman trying to live a peaceful life. I was searching something similiar to Spice And Wolf and surprisingly this one has very much in common. Shin no Nakama is lighter tho but it deosn't mean its just as any fantasy/isekai these days. There is in both some drama, romance and "working thing" (dunno how to describe it in English). I tell ya - if u enjoyed one of them you probably enjoy the other one. I higly recommend them both! 

in both, we follow the MC who's got banned from the hero's party.  

Similarities - Both MCs are/were heroes - Both MCs leave the hero party and pursue a quiet life - Both MCs open up a business - Weird strange of events occur at this new business and MC has to adapt Differences - hero's party MC is kicked out of the party VS Yuusha ni MC finishes his hero duties - MC in hero's party runs an apothecary VS MC in Yuusha ni runs an consumer electronics store 

Main characters are pharmasists, who run their own pharmacy, with help of friends 

Protagonist establishes a business in a remote village. Has mostly a SOL feel with some adventuring and fights. 

The premise of the MC wanting to live a quiet life is similar, the difference being one is a Isekai and the other one is a Fantasy anime. If you liked the slice of life and romance aspect in "Banished from the heroes party" you will like "Lv2 cheat skill". Both start sort of the same being banished to a remote village/place and with these circumstances they make the most of it by living a quiet life without wanting glory nor power. Lv2 cheat skill does have some decent character development between MC and FL. It´s really nice to find shows where the MC isn´t scared of women nor is he too afraid to take the next step. This anime does have a bit more action compared to "Banished from the heroes party" and although it may be cliche in a some Isekai aspects it´s quite enjoyable to watch specially because of Fenry`s. Her relationship with Flio is pure bliss, the comedy and character growth between them is quite similar to both Red and Rit´s. Story wise "Banished from the Heroes party" is better compared to "Lv2 cheat skill" since "Lv2 cheat skill" being an Isekai it does have some some cliche themes like being OP right from the start, having to deal with the demon king, etc. However compared to the rest, by having that slice of life, charismatic charcater and decent comedy touch is makes it distinct from the rest of generic one season Isekai shows. I would recommned reading the manga for "Lv2 cheat skill" since I believe it´s a better adaptation and covers a bit more than the anime, however overall the anime itself if pretty good and having that banger of OP it makes it better. read more 

MC gets booted from the hero's party. The hero party's performance greatly suffers while MC lives a better life with a bunch of girls. They booted the best tank in the world and the one in charge of logistics, what did they expect. 

Similarities - Both have characters leave/quit the Hero's Party/Duty - Both characters were forced out against their choice - Both is about their life after Heroing, and about doing what they wanted to do instead - Both is about the Hero's duty to the people they serve versus no longer wanting/able to do so - Both is about relationships with other characters - Both have periods of slice of life/light comedy, and more serious moments Differences - Banished by the Hero's party is mainly slice of life light romance with some serious stuff tacked on. I'm Quitting Heroing is mainly comedy and some serious themes woven together well, and helping/teaching other characters while forming strong relationships with them - Banished seems to be about defeating the Demon Lord or perhaps the god that bestows blessings forcing fate onto everybody. I'm Quitting is about joining the Demon Lord's army, and struggling to follow or break the "fate"/role one has - In Banished, storylines seem to fall apart towards the end like some things were made up as it goes. In I'm Quitting, episodes seem to be made up as it goes, but by the end it's clear everything was planned out, and well executed - In Banished, the one banished and the hero are two different characters. In I'm Quitting, it's one character.  read more 

both have op protagonist who just want a break from things and want do slow life stuff. but end being dragged by the side characters 

Slime Taoshite 300-nen, Shiranai Uchi ni Level Max ni Nattemashita I've Been Killing Slimes for 300 Years and Maxed Out My Level Is very similar to this show. Similarities: Powerful people wanting peaceful lives. Homely feeling and helping people around Protecting people trying not to be OP Stories are very different though but the protagonists can be similar  

Similarities - Both MCs leave the city and try to live a quiet life in the county side (gardener/chemist) - Both MCs are powerless in their current world - Both MCs isekai from modern day Japan/China to fantasy world - Both MCs become center of attention after an event Differences - MC in hero's party is knowledgeable about medicine VS MC in Spirit Seed Manual is knowledgeable about the typical isekai - MC in Spirit Seed Manual gets caught up with powerful beings VS MC in hero's party lives quiet life with the people in his village - MC in hero's party hides his powers VS MC in Spirit Seed Manual has no powers  read more 

The relationship in both is unbelievably wholesome. It's not every day both couples get an equal amount of respect (although to be fair, Shin no Nakama does a better job than Senko-san). Whilst they are, indeed, both vastly different stories, one cannot deny the impeccable relationship present. From good communication to understanding one another to get through with daily life, these two anime know what it is like to have a great pairing that not alone works well, but makes your heart go doki-doki. I guess the only thing to be aware of though, is that Senko-san is far less romantic compared to Shin no Nakama. What more do you want? read more 

both a similar vibe. slice of life in another world. 

Ok, this recommendation is a little out of place, but I am here to share the message that both these anime contain wholesome and very real relationships between two equally important characters. Not something is seen every day. Watch for a great romance anime <3  

I can name a few things similar of both series: Fantasy world where Demon Lord and The Hero destinated to fight each other, Plot progression and the appearance tendency of the plot, I-have-watched-for-the-plot, loveable characters, comfortable enjoyment, calm world building,... I would recommend one to the other's fans. 

Similarities - Both MCs underestimate their strength/hide their powers - Both MCs want to live a quiet life away from conflict - However, both MCs find themselves as a target of trouble and conflict Differences - Daily life of Immortal King is in a chinese, cultivation universe VS Banished from hero's party is in a fantasy/RPG universe. - Daily life of Immortal King MC is a god who studies at a cultivation academy VS Banished form hero's party MC is an adventurer who was exiled from a powerful team now runs an apothecary. 

Similarities - Both MCs have exceptional talent for their circumstances - Both MCs are considered failures and are exiled - Both MCs live a quiet life away from 'conflict' - Trouble eventually finds them again and their quiet lives slowly end Differences - Rakudai is set in a magic academy for girls VS Banished from hero's party is set in an apothecary in a quiet border town. - Rakudai is about magic warfare VS Banished from hero's party is about medicinal remedies/drugs 

Powerful underdog mc doing cute things with thier lovers and figuring out their own strength.