Since many other reviewers have gone and given a lot more detail I'll keep this short by saying it's a excellent anime series and here's my short review.
Chrono Crusade is based of a manga, which I highly recommend everyone reads, because it's even better than the anime. The Anime follows Chrono a demon and Rosette a nun around on their journey trying to find Rosette's brother Joshua. The adventure take them to new characters, like Azmaria, and Satella. The final six episodes are truly some of the best anime you'll ever see. The pure emotion put into the last six episodes was amazing, and the final episode was just so sad to watch. If anyone likes a show about many things including religion, love and friendship this is for you, but let me warn you don't expect a happy ending, but then ending still won't let you down either.