Kare Kano's strong point is its characters. They can laugh uproaringly and get a runny nose when they cry. The thoughts that cross their minds are thoughts you and I have had, maybe late at night just before falling asleep. Their worries feel real.
There is no antagonist in Kare Kano, not really. The antagonists here are the hidden demons inside each character (particularly our lead man, Arima).
My only complaint woud be the lack of an ending and the animation which could be very trying at times (budget issues).
Overall, Kare Kano is a really beautiful romantic shoujo anime that represents the best in the genre.
