Gyo, in effect, captured the essence of the manga without falling prey to the issues that plagued it. The justaposition of humanity and monsters was done more appropriately than the manga -- by splitting Kaori's character into 3 different girls, the characterization becomes far more complete and powerful. The struggle between Aki and Erika shows the inherent issue of morality in an immoral world.
Furthermore, the choice to change the lead from Tadashi to Kaori was also in good taste. Despite the overt sexual overtones present in all of Ito's work, Kaori's characterization lacked a "feminization". What we were left with was a strong female lead, and one that stood up to challenges and outdid her male counterparts. This deliberate change turns the tone from typical to unique, even among the current crop of anime that features 'Strong female leads.' It takes the female isolation from Uzumaki and Tomoe and manages to adapt those feelings into Gyo's position, strengthening the work.
The voice acting, as well as the Animation is strong. While it's not the best I've seen, it stands above most typical standards and along with Fate/Zero manages to be ufotable's "Worst" work -- Which is to say, they are massively above standard.
Gyo is the best adaptation of the manga we would ever hope to get. Thematically it is closer to Uzumaki, placed as not only a female-centered love story but a story of hopelessness. The last line mirrors a hopelessness throughout.
"I've gotten used to it."
