Before getting into it i'll admit this review is biased due to sentimentality, this is the first manga I read completely in Japanese (I suggest you make it your first as well as it is very understandable while still introducing a fair bit of vocab) so naturally I spent a lot more time on it than most manga, and associate it with good memories.
Still, there's a good reason よつばと！ doesn't have a single bad or even mixed review on MAL, and that's because it's damn great. Almost every single chapter is hilarious and memorable, Yotsuba herself is an adorable true to life portrayal of a dumb kid, the other characters are also well written and bounce off each other fantastically, and there's basically not a single thing wrong with it. It's the kind of manga only someone actually interested in people could write.
The art is cute and expressive, often there are pages with few to no words that just let the excellent panelling flow take the storytelling wheel. While the art is usually simple and efficient as befitting a comedy SoL the artist will flex and draw beautiful architecture and nature just because he can.
I could keep going but honestly よつばと！ doesn't need me to praise it. It's great, you already knew it was great, an entire website of degenerates even has Yotsuba as their mascot and one sacred cow because it's so great, go read it (In Japanese) if you haven't already.
