* MASSIVE SPOILERS! * This is purely my opinion on the ending(s), it is not meant to be a comprehensive review. Treat this as the ramblings of an awestruck kid who hastily jotted down his thoughts as he finished the manga.
So here we go:
I believe the two routes to be the author's answer to "What is Love?", but as two forms.
Ririna, whose love began as a rabid curiosity for an emotion she didn't believe she possessed, grew into a painfully intense love for Yukari. Her love mirrors her sincerity, and she never shied from her feelings once she realized she couldn't run away from them anymore. She spent her days in angst, bracing herself for the eventual rejetion (in her mind, at least) by the man who taught her how to see color in her dull world. Ririna's route is a portrayal of mature love, of selfless love. Ririna loved Yukari unconditionally, fully expecting her love to never bear fruition from the other party. Her expressions in the final chapters are gentle (in contrast to Takasaki's first turbid ones), but they are set ablaze when her love is fulfilled. The timeskip is five years later, more than Misaki's two years, which further strengthens the idea that their love will stand the test of time; a peerless Yukari marriage as calculated by the government.
Misaki's love is tumultous; her love for Yukari is passionate, and I'd go as far as to call it blinding to her. It brought her out from when she was at her lowest, and her heart now beat solely for Yukari. She did not hesitate to make THE choice, damning herself to a life of pain. Time might have mellowed her passion, but I personally believe that's naivete. Misaki's love bloomed the more she was with Yukari, and even though it's was a love destined to shatter, the dazzling light of that glass-like passion strengthened her feelings for him - a love very reminiscent of youthful love. She fell for him harder and deeper. Her route's chapters show us how her love warped her; she hated one of her closest friends, she hated the one for whom she lived her life. But Yukari faced her head-on, and in what can only be termed as immature recklessness, chose his present impassioned feelings over a future that was guaranteed to be a fulfilling one. He took her resolve head on, clashing against her torrentious feelings, and finally breaking through the fears Misaki held.
But is that really wrong? Is it wrong to choose an immature love, which held even the possibility of death, over a safe future? I believe Misaki is the author's answer to a love that simply cannot come true. There are too many factors at play which make choosing Misaki a 'mistake' - but can you deny the strength of your feelings for a person you longed for nearly every waking moment since you met them? A 'wrong love' is a nonsensical idea. There is no guarantee Misaki and Yukari's love would work out; but is there a guarantee that it won't? If I wanted to come out of my stupor after reading this intense piece of literature, Ririna's route is the only one that I would accept. But, like Misaki's love, my feelings towards her emotions are as intense as they can ever be, fleeting as they may. My tears held the same weight as they poured out of my eyes when I was swayed by both of the girl's emotions.
Koi to Uso is a wondrous portrayal of love, one unlike anything I've ever experienced before.