I would like to say "Itazura na kiss" is the best anime with the most perfect and happy ending.
The anime is really different and unique.
The plot moves on Kotoko , a girl lacking so called qualities for being a perfect women , having a crush on most popular guy of her school, Naoki Irie. Though Irie pretends to hate Kotoko, he is deeply in love with Kotoko.
After many struggles, they get married . Then the story continues about the struggles in their marriage life .Then they become parents of a girl .
I think everyone would like the perfect anime with happy ending.