It's important to know the context of this series and to know at least who Hideaki Anno when watching this. Of course, it isn't and shouldn't be required, and can be enjoyed as a light commentary on otaku lifestyle and can be enjoyed as a nice laugh.
For one, it's absolutely criminal that this series has such a low rating. (probably rated so low by ignorant idiots who hate anything unconventional.)
This anime accomplishes exactly what it set out to do: accentuate and describe Hideaki and Moyoco Anno's married life for a few laughs (if not tons of them). It's certainly not meant to be taken seriously or critically analyzed, as this series is purely for a very, very, very niche audience, so I understand if one would be confused if they were new to anime.