A master comedy? Why yes, it is.
Ichigo Mashimaro has an unusual sense of humour and that will be noticeable right off the bat. The story is dependent on timing and the subtlety of the humour. While there are instances of pure crazy slapstick, most of the comedy comes from the sarcastic remarks or the feeling of "yeah, life's like that" aspect of it.
The characters completely complement the show. There is Miu, the show stealer who is insane and has ADD, I'm sure of it. Then again, the girl doesn't forget and holds madly funny grudges, so maybe she has selective or self-inflicted ADD. Her best friend is Chika, a normal girl who gets pissed off for being the only sensible person out of all her friends. What makes Chika great is her chemistry with Miu. They make a good comic dup. Sort of observing everything is Chika's older sister, Nobue, a college student who drinks, smokes, and loves "moe". Additionally, there is Ana, a British girl who can't speak a lick of English and Matsuri, the resident moe blob who can barely stand straight far less function properly in society.
The jokes are hilarious and tight, the concepts are unual though normal at the same time, and there's also a bit of emotional, real story in between all the comedy.
Ichigo Mashimaro is a great series, and highly recommended.
