I know that writing a review after only seeing 10 episodes isn't really fair. But I just thought I'd share my opinion on it.
After watching and entirely loving Fullmetal Alchemist I decided to watch Brotherhood. The very first scene was entirely different, and this continued throughout the rest of the episodes that I watched. After coming from FMA, the change in character behaviour and attitude was a complete shock. I couldn't bring myself to watch the rest of the series out of fear of ruining FMA completely.