I expected Blood-C to be one of the best anime of the season. I really did.
Unfortunately, you grow tired of the whole charade within the first two or three episodes. It might have worked if it more time (say 24 episodes) but it was definitely not supposed to be squeezed into 12 episodes. As a result, you have an anime that goes slow at the beginning and you barely know what's happening in the last couple of episodes.
Well, it is Clamp, so the art is pretty nice. Gore isn't their forte, but I can't blame them for experimenting. The OP and ED themes aren't bad either.
If you're looking to watch this anime because you liked Blood or Blood+, then don't. You will hate this series. Take my word for it. If you're more open-minded about it then go ahead and watch it, but you will still probably hate it.
This anime is definitely not for children, and the grown-ups would do well to avoid it too. You have been warned.