GITS Innocence is very much spiritual successor to the original GITS film, at least in terms of presentation of storyline and interspersion of philosophy.
Innocence is a film that will appeal to some people, but others will either find the story too lacking or smothered with philosophical guff. To be perfectly honest I found the story to be extremely simplistic and shallow, there really isn't much depth here unless if you look to the quotation of classics or philosophy as depth. Almost all of the dialogue in the film is devoted to quotation, it becomes quite tedious after a while - not least because there isn't much necessary framing for those quotations.
The supposed point this endless quoting is to question artificial concepts that have no real bearing on our world, so it ultimately feels rather pointless.
Visually the film is... inconsistent. The 2D artwork is beautiful and fluidly animated, yet it is constantly at odds with ugly 3DCG artwork. Normally I wouldn't be quite so bothered about this, my complaint here is that excessive screen time given to ugly 3DCG panoramas and sweeping shots of things-which-aren't-very-interesting. Long story short, Innocence is not as visually impressive as the first GITS film.
It's a shame that this is such a disappointing film, but if you really want to try something deep try reading the many works cited in this film.