Let me the voice of dissent and declare that Dorohedoro is crap! I mean it.
Every episode is filled with stupid "comic relief" and absolutely unessential character interactions which do not help the series at all. About half the things that go on in the show has no connection to the main plot. No story whatsoever, only glimpses of a promised plot that never really makes it into the show. I don't know if the studio was having money problems or not but I think they forgot to hire a character designer. None of the characters have any real motivation and their choices are plain irrational. Terrible world-building, if there is any world-building at all. As for the plot it started out original, then got stale from the 3rd episode, and by the 8th episode was all over the place which is how it stayed till the end with some new info crammed into the last episode so we tune in for Season 2. I'll pass.
About the violence and gore and stuff it is just for show and only skims the surface. Watch some 70's anime if you want violence and gore. Despite its hype I failed to notice any original or dark themes. "Ohhh some evil people are killing us and we have to fight to survive, while figuring out what is going on"- is almost every anime ever.
People going on about how good the animation is has no clue about animation. They just saw an unique look and feel and went Woaahhhhh! The fight scenes are plain disgusting. Btw similar visual tones can be found in so many older anime- check out Paprika, Devilman, Blood+, Kagewani etc.