Watch this if you are a Blame! fan, just don't watch it with the intent of getting the same experience you got from the manga.
While not being entirely true to the original story, I can't really complain. This was spectacular... The music, the sounds, how everything looked, it was all so cool! I'm sure if you're one of those super picky fans that rip anything that's not exactly the original story you will find a lot of things to complain about. Also I know lots of people are not fans of the 3D art style. Quite frankly I think it fits it well.
In any event... I would not watch this until you read all of or some of the manga. To me this is just the icing on the cake to Blame! My one complaint is that I wish it was longer and spent more time around Killy. Time to read the manga again...
EDIT: If you have never read Blame! I would actually recommend you to watch this... Then if you think it is cool, read the manga!
Sanakan and Cibo are honestly adorable and Killy is as bad ass as it gets... nuff said
2019: Im still re-watching this movie every couple months... Its a good ass time! Can't wait for my next Blame! manga re-read.