 If you liked
Mushishi
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 ...then you might like
Tousei Gensou Hakubutsushi
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Although Tousei Gensou is somewhat dark when compared to Mushishi's relatively easygoing tone, both have a protagonist who deals with episodic (usually single chapter or small arcs) supernatural cases he is unusually knowledgable about. Both also delve into the protagonist's past and eventually explain how he came to be the way he is.
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Recommended by lithiumflower
Both are episodic, and both main characters help people deal with strange occurrences. Both main characters are also fairly solitary, though Ginko of Mushishi travels while Shinobu of Tousei is based in an antiques shop.
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Recommended by Kyojinslayer