 If you liked
Yu☆Gi☆Oh! Duel Monsters
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 ...then you might like
Dr. Stone
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Both series feature savant's and genius/prodigy main characters with great & unique hair. Both are based off popular shonen JUMP manga. Main cast of characters are of similar ages (high school ish) and also had almost ordinary school lives where they made some of the friendships they maintain on these extraordinary adventures. Both series also have amazing art styles, character designs and OST's.
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Recommended by JVskunkape
Both have spiky hair mcs and a ya cast,friendships and rivarlys,mind games and interesting artstyles and character designs too.
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Recommended by Disapeared_Ghost
Rivalry. Although plots aren't greatly similar. Dr Stone and Yu-Gi-Oh both share a similarity in characters with a strong rivalry you are waiting for to go head to head when they are at their highest; Yugi and Kaiba for YGO, Senku and Tsukasa for Dr Stone.
Both are good anime targetted for the shounen demographic, where characters use brains instead of fists. With YGO being based on a card game, Dr Stone being based on science.
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Recommended by NextUniverse