Seirei no Moribito, Made in Abyss Recommendations
Both are about a journey through strange lands full of danger and strange creatures. With lush art, and incredible story and characters. If you like one you will probably like the other.
An adventure? Yes. A journey? Indeed. Hard decisions? Yup. Monsters? Of course. Lovely characters? You bet. Tears? I'm sorry, most probably yes. A little laugh? Thankfully yes. In both cases, the MCs -along with people they care about- take a long, harsh journey in order to achieve a goal/meet their fate, something that initially appears to be impossible. Clear up your schedule, once you start following them, you'll be hooked for good.