 If you liked
Dead Dead Demons Dededede Destruction
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 ...then you might like
Takopii no Genzai
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Both heavily feature a Doraemon-like alien character and two girls are the core of the series, along with one boy as a secondary romantic interest. Both deal with dark topics happening to cute girls, too, and they share a surreal artstyle with impactful panelling.
There's also another important similarity, but it's a spoiler :(