 If you liked
Druaga no Tou: The Aegis of Uruk
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 ...then you might like
Ixion Saga DT
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Both anime has the adventure/RPG style to it, where the hero is kinda thrown into trouble in some way. Druaga's a bit more segmented since every episode is them climbing one floor of the tower (in most cases). The biggest similarity I find are the humour/gags in both stories, though Ixion's jokes lean towards the more perverted side of things. They are both extremely enjoyable if you give it a few episodes to sink in.