Fullmetal Alchemist, Scrapped Princess Recommendations
Similar fantasy-style plot with underlying sci-fi - and both reach about the same level of epic-ness by the end.
If you like well-drawn anime with stories that can be dark and light-hearted at the same time, then I highly recommend Scrapped Princess.
The best way I can articulate why an FMA fan would like Scrapped Princess is tone. You'll get very similar social commentary with the added bonus of some of the best sci fi I've seen. Let's just say it's not the standard fantasy world that's introduced early on. It's defiantly a dark one, that's for sure.