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Are about young people with super-powers, where the male lead who has to deal with his life being turned upside down, and responding to people who want to use him. Both have a good deal of action, and LOTS of violence, blood, and gore. E's is more horrific. X has more drama. Similar art style; X has a more feminine aesthetic. 

Same background info about people changing into "mutants" with abnormal power being cast out from society and going through similar treatment to be used as pawns, pursued, etc. Both are very good. :)