Jikuu Tenshou Nazca

Both animes focus on the relations between a sensei and a pupil. When the teacher chooses a path that will bring destruction to the world, the pupil has to make a difficult choice of stopping him by any means. 

In both animes the characters find out that they are reincarnated spirits of people who died a long time ago, and their relations in the past affect their present life. There is yaoi in Mirage of Blaze and no yaoi in Nazca but the relations in Nazca are also very emotionally charged.