 If you liked
Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen
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 ...then you might like
Kusuriya no Hitorigoto
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Both stories are about young women who seem to have more knowledge then the people around them. They use their extensive knowledge to heal, create invention, and solve problems. They're both very intelligent and use their knowledge or their friends/family.
Switch the place of an Apothecary and an wannabe Librarian and you get Honzuki as kusuriya equivalent. Honzuki has Isekai elements, magic powers and Western scenario but both of them have brilliant protagonist that literally change the world around them, conducting innovations even when their resources are limited, that being related to the current technology or hierarchy/social barriers. All of those themes are common in one and another. The protagonist are really passionate about their on areas of expertise and that make them really intriguing. Also, curiously, both of them have similar casts roles in the side characters roaster which made me baffled... I literally
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Both stories present strong, intelligent, curious female protagonists with a collection of very specific knowledge in their areas of work. At the same time, they develop as people in socially complex and ancient environments while developing interpersonal relationships and growing as individuals when facing various situations that challenge them.
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Recommended by Marcelo_Flores
In Ascendance of a Bookworm, the female protagonist loves books so much that it can change her behavior in the same way that rare ingredients and poisons affect Maomao's behavior. This special detail works throughout the series. In both, there is an aristocracy and its interaction with each other and with commoners.
The beginning of the story of the Ascendance of a Bookworm is not so similar to the The Apothecary Diaries, but then the similarity increases greatly (I read the ranobe of the Ascendance of a Bookworm after season 3).
If you are ready to read the sequel later (and if you are not from the
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