 If you liked
Sen to Chihiro no Kamikakushi
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 ...then you might like
Hanasaku Iroha
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In both animes the protagonist is a girl, who used to have a normal life, but who now finds herself working at a traditional in to earn her living. Both of them have been seperated/abandoned from their parents and are having trouble adjusting to the new way of life in the beginning.
Besides that, both protagonists are hard-working and tries to do their best in order to help others. This was my impression after only 1st episode of Hanasaku Iroha, though :)
the personalities of both protagonists are almost alike and it's also about working at a traditional style hotel--in spirited away it's bath house and in hanasaku iroha is a hot spring hotel--both with cruel owners.
These two animes are both very similar, where both protagonist are forced for work a an in, regardless of their bad situations, they do their best the make the best of it, and on the way they make friends and have a good time
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Recommended by Halfblackninja
Both animes include a female protagonist that have to leave their usual life to work in a 'bath house'. Both include a horrible grandmother like authority figure in charge of the bath house/inn. Overcoming challenges and at first being rejected by their peers, they end up being welcomed and loved by their new friends.
Spirited Away provides a lot more fantasy content, whereas Hanasaku Iroha brings you comical situations and interactions. Both are light-hearted and great animes to watch.