It has story elements like that of Dragon Ball when Goku meets Bulma (a human girl) for the first time and is foreign to many things outside of of his domain and it has a familiarity to that of One Piece's main protagonist: Luffy's personality and behavior (hate One Piece during the Zou arc) all which are associated with this manga's protagonist Shiki, and many references to Hiro Mashima's Rave Master and Fairy Tail (not into this series) mangas and outside references to games like "Dead by Daylight" and popular social media sites like "Youtube".
However, one down side to this manga after reading up to at least 44 chapters before i dropped it again, and doing some spoilers on later chapters, i started noticing the overly sexual appeal of the female characters which was making me feel uncomfortable, you'll see most of the fights in the manga scans where the female characters show a LOT of underwear shots, and manga scans showing them naked in different positions whenever they're in the bath. it's practically more of a hentai honestly, i don't know where Hiro Masashi's brain went after Rave Master but, Eden Zero is not a good manga to take seriously without the constant sexual content and male characters who even act perverted when they see the female characters look half naked most of the time.