Aggressive Retsuko is about a red panda office lady that relieves stress by singing death metal. That's all you need to know.
All the characters are anthropomorphic animals, and I think that's quite charming. Retsuko is basically the cutest thing ever when she's not screaming death metal.
The humour is alright, managing to make me smirk a few times throughout the ten episodes I've seen. One could say this is a family-friendly version of Detroit Metal City - though a family-friendly version of DMC is not DMC at all.
The episodes are only a minute long, so you may as well give it a shot.