STORY
I was very disappointed in the story for a lot of reasons. It progresses painfully slow, and the character development eventually drops just about everyone in the 'gray area' between good and bad. So basically by the time the climax comes around you have nobody to root for. You don't care if any of the main characters survive, shiki or human.
ART / SOUND
This is what ruined it for me. I probably would have enjoyed the story more if the art wasn't so ridiculous. The hair on some of the characters...the hair. It's like Super Saiyans on crack. Gravity defiant, logic defying hair that makes the living humans look undead even though they're still alive. The elderly and even some of the young characters (Masao in particular) look hideous right from the start. It's not scary, in my opinion it's just unpleasant to look at. There's not much to say about the Sound. It didn't really leave an impression. The sound effects weren't always used the best way (I.E. Excessive cracking noises coming from a Shiki that is barely moving it's neck)
CHARACTERS
A lot of the characters are so incessantly obnoxious to the point where you want them to die. Then they die. Then you realize crap this is Shiki, I have to wait for them to die a second time before I'm through with their BS. Even the characters you like in the beginning betray those good qualities by the middle / end. One more thing, chain smoking doctors aren't cool. You're supposed to be a doctor dammit, save those cigarettes for us non-doctors.
CONCLUSION
Shiki failed to live up to my expectations. I feel like Shiki never intended to give you a likeable cast. The point of the story is to submerge you in moral ambiguity with a bunch of mediocre characters and slow moving plot. Most likely the goal was to have the viewer ask him or herself in the aftermath of the climax "What was (morally) good? What was bad? Was anybody really in the right?". It's left up to the viewer to decide without the anime deciding which side was 'right' for you. Unfortunately, at least in my case, by the time I got to that point I didn't really care enough about the story, the characters, or the ending to think too hard about it.
