I was told that this was a very stylish, very gory anime. It was recommended several times to me, but when I got round to watching it, I was appalled at the terrible, nonsensical story.
First of all, the story as a whole is VERY mediocre: boy loses father, boy gets revenge on fathers killer, etc. It's like something from Daredevil. But the thing that really, REALLY pisses me of is this: he hardly ever fights humans. Seriously. He fights killer robots, humanoids and weird monks (one armed with a bazooka!), and finally a guy with 3 arms.
That is why this series comes off as poor.
However, this is saved by the excellent animation with unique styling and excellent sounds. The artwork is great, and the voice acting by Samuel L Jackson adds the extra bad-assery that the show needs.
The charaters were pretty bad. You know how I feel about the enemies, but even Afro-Samurai is badly portrayed. He's a 2D character, and the writers thought that if loads of bad stuff happened to someone, I'll automaticly feel sorry for him and be on his side. No, it doesn't work like that.
Overall, not a series worth avoiding, but only because it's so short. There are plently of better anime to watch in the mean time.