 If you liked
Gun-Ota ga Mahou Sekai ni Tensei shitara, Gendai Heiki de Guntai Harem wo Tsukucchaimashita!?
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 ...then you might like
World Teacher: Isekaishiki Kyouiku Agent
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1) Both main character reincarned in another world
2) Both main character preserve the memories of his previous life
3) Both main character experimented with magic/ science
4) The best friend of the main character are a demi-human
5) Both story are set in a fantasy world
6) Both main character are bred in a orphanage