Nana, Otona Joshi no Anime Time Recommendations
Mature, thoughtful stories about adult women living in contemporary Japan. Neither show shies away from realistic depictions of romance, sex, and failed relationships. Both have a strong sense of melancholy interspersed with levity at life's absurdities, and their protagonists make difficult and interesting decisions. Nana is long and lacks a conclusive ending; Anime Time tells four unrelated short stories. In each case it's less about the destination than the journey.