Mujin Wakusei Survive, Mouretsu Pirates Recommendations
Optimistic far-future adventures that star surprisingly good-natured, competent teens who face myriad tribulations in outer space. They both blend comedy and drama with very little fanservice or stock anime tropes. Both shows have mixed gender casts with female leads. Both feature a protagonist and supporting character with something of a teenage girl Kirk & Spock dynamic - a charismatic, courageous leader and a level-headed, logical second-in-command. Neither show has much romance. Pirates comprises several distinct arcs that mostly involve spaceflight, while Survive follows a continuous narrative about survival on a hostile planet.