Aa! Megami-sama! (TV), Ookami to Koushinryou Recommendations
Both animes involve people from separate worlds how fall in love with each other. They face trials that can either strengthen their relationship or break it apart.
An honest man finds companionship in a supernatural woman. As they get to know one another better, they gradually fall in love.
More importantly, both address that feeling of loneliness and ennui that many young men find themselves struggling with when breaking into the workforce for the first time.
Two series for anyone who has ever thought "If I just had an awesome girlfriend, my life would be totally different..."