Toradora!, Imouto sae Ireba Ii. Recommendations
Toradora & Imouto sae both contain the same "Scrubs" - style formula (the irl comedy, occasional emotional doctors show). Namely, they're a) character driven b) part 1 of episode of characters interacting/doing trivial things c) part 2 of episode containing the "feels" / life lesson.
a large lesson that is constantly revisited is that of "taking something for granted" whether it be a talent, a personality, a relationship, etc. consequently, each of these shows also delves into when those characters does take something for granted and how it affects the rest of the cast.