Akagami no Shirayuki-hime, Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen Recommendations
Both female protagonists love knowledge, are smart, and have a good heart. They use their skills and passions to improve their lives. The shows have similar atmospheres where you can relax and enjoy the beautiful worlds. Both have great characters and world-building, and are well-written.
Both mcs are female, both of them are in a fantasy world shirayuki is not an isekai however. while honzukismc aspire to be a librarian and make books, shirayuki aspires to be a physician (think herbal medicine etc) . overall mood of series is similar