Genshiken, Lucky☆Star Recommendations
Both depicts deeply in Japanese culture in both a humorous and true way.
A must watch!
Both have a lot of humor, references to another animes, and otakus! =)
Both animes deal with the topic of otakuness and subtopics like games, manga, anime itself, cosplay, soundtracks and what not. Genshiken can deal with the topics in a serious way, creating an ambiance of pride and what not, and Lucky Star derives the topic into a silly story of life, more for the sake of the viewers' laughter.
Genshiken is a more serious and realistic version of Lucky Star, although focusing on male characters. Both series deal with "Ero-games", although they are more "featured" in Genshiken.