Blood+, Kyuuketsuhime Miyu (TV) Recommendations
they are the same..! the girls are fighting their destiny with the guy, (friend.,chevalier.knight.watever!) who's ready to protect them and do what the girl wisHes..
a girl and her companions fight monsters (technically her own kind). both vampires.
They both deal with vampire/demon like main characters who's mission is to destroy an evil race that is plaguing human society. The main characters both love their "helpers" but feel that it is impossible to be in a relationship with them.