NHK ni Youkoso!, Uzaki-chan wa Asobitai! Recommendations
These anime both follow a protagonist who is a shut in and anti-social with a girl trying to break them free of that. However, the method by which the girls help the protagonist is very different. NHK is a little more serious with the protagonist's anti-social behaviour preventing him from even leaving his home while Uzaki-chan is more lighthearted and fun (with a dash of ecchi). Both of them also share the genres of Comedy and Romance!