Minami-ke seems to be the twin sister of Today in Class 5-2. The most striking similarity is the "serious face" - i.e. when something weird/shocking/appalling happens, the faces aren't animated in the usual moe/loli (or whatever) idioms.
There's plenty of witless humor to go around, and a lot more pedo-fanservice as well.
The Minami-ke fan may be disappointed since there isn't really a Class 5-2 equivalent of Chiaki (there is a Chika, though), nor is there a Haruka, or any high school persona at that, but the cast is "diverse" enough to fulfill all the general archetypes as to not leave the viewer in rage at all.