Overlord IV

Extreme utilitarian gets isekai'd and commits war crimes they believe are justified means to get to their goal. 

MC dies and reincarnate as slime. Make loyal subordinate like OVERLORD. MC is overpowered 

Isekai with Demon Lord type MC. Bunch of hotties around too. In my opinion this is the closest one out of all other recommendations. Main difference is that Overlord build around MC that resides mostly in his base while Isekai Maou more of traveling party type anime.  

Mc overpower,Mc is Skeleton 

They are both iconic game isekai's with a well defined atmosphere where the main character is pretty much overpowered and takes part into the conflicts of the game world.  

Overpower MC, no childish Shounen MC, Demon Lord MC or you could say the God of Death. Yeah they're really similiar. But the difference is Overlord has an inner monolog that MC voice from the real world, this thing make him not fully serious kind of character.  

Sometimes it is best to break off all gaming activities especially when an obsession goes beyond a perilous point. However, the thought of turning everything one has ever achieved into nothingness is hard to bear even for the strong-willed.  

Game mechanics are important as the setting of the animes. They place importance on life or death in HP, and remain as a character's lifeline throughout the whole anime as a game mechanic.  

These 2 anime has similar situation in which both the protagonist and others are stuck in a rpg game with no knowledge on returning to the real world. However, in Overlord the main protagonist is the only current known player who's stuck while in log horizon many players who were logged on at the time was transported into the game. Also, both protagonist are overpowered.  

How to Pick Up Girls is not clearely a trapped in a game anime, it sure feels like one. Overlord is a trapped in a game anime. Where both have common ground is that they both accept the world they are in as is and make the most of it and don't treated it like a game.