I'll admit that upon starting the show I was a bit apprehensive myself, but by the second episode I was hooked. The thing that probably turns most people off- the art style- quickly became one of my favorite things about the show. The style, which manages to be both realistic and surrealistic, fits the show perfectly, and I can hardly imagine any other style working as well for this series.
The show is episodic in format, with each episode following a different patient of the eccentric Dr. Irabu. In each episode, Irabu's assistant, Mayumi, gives each patient an injection which usually temporarily turns them into an animal. In any given episode it's not uncommon to see other patients and events from past episodes transpiring in the background. The different patients' cases are all very interesting and sometimes even touching, and the resolution of each episode feels satisfying and complete.
Without a doubt, though, my favorite part of the show was the two recurring characters, Dr. Irabu and Mayumi. At first I figured Irabu and Mayumi would be static characters who were simply there to spice up the show. This is not the case, though. I was delighted to find that we actually discover a few things about Mayumi and her personality, and I ended up really enjoying her character. And I think it's safe to say that Irabu is the driving force of the show, helping his patients work through their problems in unconventional but effective ways and just being delightfully strange in general.
I would say the art and characters are the most outstanding parts of this show, but it should be noted that the voice acting and opening and ending songs are excellent and that the show is just really enjoyable to watch altogether. It's sad that a show this good isn't talked about more.
