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I find Hyuuga Natsume very similar to Sohma Kyo. Abused, an outcast (in a way), and "different." Also, they're rude at first, but later on, they softened up and changed in various ways. Sakura Mikan is also quite similar to Honda Tohru. An airhead, and simple-minded. She's also the "key" or the "cure" to Natsume (in Fruits Basket, Tohru was Kyo's cure). Of course, I wouldn't leave Nogi Ruka behind. He's similar to Sohma Yuki because he's gentle and admirable. He and Natsume are opposites, like Yuki and Kyo are, although the relationship between Kyo and Yuki is nowhere near Ruka and Natsume's.