Danzo Shimura is one of the oldest villagers in Konohagakure, a war hawk who believes that all of the former Hokage have placed peace above the village's best interests. He was one of the elders who orchestrated the Uchiha Clan's demise. The right half of his body is covered in bandages to hide a damaged Sharingan eye transplanted from the body of Shisui Uchiha, as well as the vast amount of Sharingan eyes grafted to his arm. He also had himself injected with the cells of the First Hokage allowing him to use the Senju Clan's unique skills. He was once considered for the position of Third Hokage, but that title was given to Hiruzen Sarutobi whom he served as an adviser. Since then he has been using The Foundation, his own personal black ops team, to secretly ensure he would become Hokage.
Throughout Part II, Danzo has been at odds with Tsunade and acts on his agenda of killing off Sasuke in secret. But after Konohagakure is destroyed and Tsunade is left in a coma, Danzo finally convinces the Fire Country's feudal lord to make him Acting Candidate Sixth Hokage, using his new found power to have the ninja track down both Sasuke and Kabuto, the latter in order to restore Shisui's eye. However, while at the Kage conference, Danzo is forced into fighting Sasuke. He dies shortly after Sasuke mortally wounds him with his lightning technique. In the Japanese anime he is voiced by Hiroshi Ito.